TGF-beta RIII Polyclonal / Unconjugated /

Product Details

Description	WB: Preliminary experiments gave an approx. 38 kDa band in human placenta, lymph node, and tonsil lysates and in lysates of Daudi, Jurkat and MOLT4 after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 93.5 kDa band according to NP_003234.2. The 38 kDa band was successfully blocked by incubation with the immunizing peptide.
Conjugate	Unconjugated
Clone
Target Species	Human
Applications	ELISA
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About TGF-beta RIII
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]

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