BID Polyclonal / Unconjugated /
Product Details
| Description | Peptide ELISA | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Human | |
| Applications | ELISA, WB | |
| Supplier | ||
| Catalog # | Sign in to view product details, citations, and spectra | |
| Size | ||
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| Antigen | ||
| Host | ||
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About BID
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Aug 2020]
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Aug 2020]
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Validation References
| PMID 15827557 | |
|---|---|
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