CD8a / DyLight 405LS / C8/1779R

Product Details
Description Protein A purified
Conjugate DyLight 405LS
Clone C8/1779R
Target Species Human
Applications FC, ICC, IF, IHC-P
Supplier
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About CD8a
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Experiment Design Tools
Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

3339 CD8a antibodies from over 46 suppliers available with over 184 conjugates.

 Compare