Pax3 / NL 557 / 274212
Product Details
Description | Human/Mouse Pax3 NL557 MAb (Clone 274212) - | |
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Conjugate | NL 557 | |
Clone | 274212 | |
Target Species | Human, Mouse | |
Applications | ICC | |
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Catalog # | Sign in to view product details, citations, and spectra | |
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About Pax3
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]
About NL 557
NL 557 from Bio-Techne is a fluorophore with an excitation peak at 557 nm and an emission peak at 574 nm. It can be used in fluorescence microscopy.
NL 557 from Bio-Techne is a fluorophore with an excitation peak at 557 nm and an emission peak at 574 nm. It can be used in fluorescence microscopy.
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