Sec8 / DyLight 488 / 14G1

Product Details
Description Protein G purified
Conjugate DyLight 488
Clone 14G1
Target Species Bovine, Canine, Chicken, Fish, Guinea Pig, Hamster, Human, Mouse, Primate, Rabbit, Rat, Sheep
Applications IF, IHC-P, ICC, WB, IP, IHC
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About Sec8
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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106 Sec8 antibodies from over 15 suppliers available with over 12 conjugates.

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