BNIP3 / DyLight 488 /

Product Details

Description	This BNIP3 antibody is useful for Immunocytochemistry/immunofluorescence and Western Blot. In Western blot a band is seen in hypoxic samples at approx. 30 and 60 kDa, representing the BNIP3 protein. There are some non-specific bands present as well. It is recommended that normoxic samples are run next to the hypoxic samples as a negative control. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Conjugate	DyLight 488
Clone
Target Species	Human, Mouse (Negative)
Applications	ICC, IF, WB
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About BNIP3
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014]

About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.

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