Serpin D1 / Unconjugated /

Product Details
Description Precipitating polyclonal rabbit antiserum to human heparin cofactor II. Heparin cofactor II is a glycoprotein synthesized in the liver and has a molecular weight of 65,000. It is a plasma serine inhibitor of thrombin. Antithrombin III is more slowly inhibited. A hereditary form of inactive heparin cofactor II has been described. Reduced plasma values have been observed in disseminated intravascular coagulopathy and in lever disease. Freund's complete adjuvant is used in the first step of the immunization procedure.
Conjugate Unconjugated
Clone
Target Species Human
Applications IEP, DID
Supplier Biorbyt
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About Serpin D1
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015]
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257 Serpin D1 antibodies from over 16 suppliers available with over 36 conjugates.

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