CD81 / APC-CF750 /
Product Details
| Description | CD81 (TAPA-1) is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It has been cloned independently several times for different functional effects and is reported to influence adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition. Similarly on T cells CD81 associates with CD4 and CD8 and provides a costimulatory signal with CD3. | |
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| Conjugate | APC-CF750 | |
| Clone | ||
| Target Species | Feline, Human, Rabbit | |
| Applications | FC | |
| Supplier | Abbexa | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD81
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
About APC-CF750
APC-CF®750 from Biotium has an excitation peak at 651 nm and an emission peak at 777 nm and is most commonly used in flow cytometry. Spectrally its similar to APC-Cy7, APC-Alexa 750, APC-Fire™ 750 and APC-H7
APC-CF®750 from Biotium has an excitation peak at 651 nm and an emission peak at 777 nm and is most commonly used in flow cytometry. Spectrally its similar to APC-Cy7, APC-Alexa 750, APC-Fire™ 750 and APC-H7
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1191 CD81 antibodies from over 45 suppliers available with over 89 conjugates.
