BID / Unconjugated / 005
Product Details
| Description | This antibody was obtained from a rabbit immunized with purified, recombinant Human BID (rh BID; Catalog#10468-HNCE; P55957-1; Met1-Asp195). | |
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| Conjugate | Unconjugated | |
| Clone | 005 | |
| Target Species | Human | |
| Applications | ELISA, ICC, IF, IF | |
| Supplier | Sino Biological | |
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About BID
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Aug 2020]
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Aug 2020]
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