CD134 / Unconjugated /
Product Details
| Description | Produced in rabbits immunized with purified, recombinant Human TNFRSF4 (rh TNFRSF4; Catalog#10481-H08H; NP_003318.1; Met 1-Ala 216). TNFRSF4 specific IgG was purified by human TNFRSF4 affinity chromatography. | |
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| Conjugate | Unconjugated | |
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| Target Species | Human | |
| Applications | ELISA | |
| Supplier | Sino Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD134
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
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