Antithrombin / Unconjugated /

Product Details
Description Produced in rabbits immunized with purified, recombinant Human Serpin C1 / SERPINC1 (rh Serpin C1; Catalog#10142-H08H; NP_000479.1; Met 1-Lys 464). Total IgG was purified by Protein A affinity chromatography.
Conjugate Unconjugated
Clone
Target Species Human
Applications ELISA
Supplier Sino Biological
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About Antithrombin
The protein encoded by this gene, antithrombin III, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. Numerous mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency which constitutes a strong risk factor for thrombosis. A reduction in the serum level of this protein is associated with severe cases of Coronavirus Disease 19 (COVID-19). [provided by RefSeq, Sep 2020]
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33 Antithrombin antibodies from over 6 suppliers available with over 11 conjugates.

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