PSMA3 / Unconjugated /
Product Details
Description | Produced in rabbits immunized with purified, recombinant Human PSMA3 / Proteasome 20S alpha 3 (rh PSMA3 / Proteasome 20S alpha 3; Catalog#15297-H07E; AAH29402.1; Met1-Met255). PSMA3 / Proteasome 20S alpha 3 specific IgG was purified by Human PSMA3 / Proteasome 20S alpha 3 affinity chromatography. | |
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Conjugate | Unconjugated | |
Clone | ||
Target Species | Human | |
Applications | ELISA, ICC, IF, IF, WB, IP | |
Supplier | Sino Biological | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About PSMA3
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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