ASAH2 / Unconjugated /
Product Details
| Description | Produced in rabbits immunized with purified, recombinant Mouse ASAH2 Lumenal domain (rM ASAH2; Catalog#50006-M07H; Thr 34-Thr 756; NP_061300.1). Total IgG was purified by Protein A affinity chromatography. | |
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| Conjugate | Unconjugated | |
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| Target Species | Mouse | |
| Applications | ELISA | |
| Supplier | Sino Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About ASAH2
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]
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