RNF7 / Unconjugated /

Product Details
Description Rabbit Polyclonal antibody for RNF7 detection. Tested positive for ELISA,Immunohistochemistry,Western Blot, in human
Conjugate Unconjugated
Clone
Target Species Human
Applications WB, IHC
Supplier Boster Biological Technology
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About RNF7
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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