PFKFB3 / Unconjugated /

Product Details
Description Anti-PFKFB3 Rabbit Monoclonal Antibody tested for for WB, IHC, ICC, IF, IP, FC in Human, Mouse, Rat.
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications FC, IF, ICC, WB, IP, IHC
Supplier Boster Biological Technology
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About PFKFB3
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
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174 PFKFB3 antibodies from over 16 suppliers available with over 27 conjugates.

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