MSH3 / Unconjugated /

Product Details
Description Rabbit IgG Polyclonal antibody for P20585 detection. Tested positive for WB IHC in Human
Conjugate Unconjugated
Clone
Target Species Human
Applications WB, IHC
Supplier Boster Biological Technology
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About MSH3
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
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