MAN1B1 / Unconjugated /

Product Details
Description Rabbit Polyclonal Antibody for MAN1B1 (MAN1B1) detection. Tested with WB in Human, Mouse.
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications WB
Supplier Boster Biological Technology
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About MAN1B1
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
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