KCNQ2 / Unconjugated /

Product Details
Description Rabbit Polyclonal antibody for KCNQ2 detection. Tested positive for IHC, WB in Human, Mouse, Rat
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications WB, IHC
Supplier Boster Biological Technology
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About KCNQ2
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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