VDAC1 Monoclonal / Janelia Fluor 646 / S152B-23

Product Details
Description Greater then 60% identity with VDAC2 and VDAC3.Detects approx 30kDa. Does not cross-react with VDAC2 or VDAC3 (based on KO validation results).
Conjugate Janelia Fluor 646
Clone S152B-23
Target Species Human, Mouse, Rat
Applications ICC, IF, IHC
Supplier Novus Biologicals
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About VDAC1
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]
About Janelia Fluor 646
Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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