SUN2 Monoclonal / Biotin / 3.1E
Product Details
| Description | Specificity of human, mouse, rat UNC84B antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins. | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | 3.1E | |
| Target Species | Human, Mouse, Rat | |
| Applications | ICC, IF, WB | |
| Supplier | Novus Biologicals | |
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About SUN2
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
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125 SUN2 antibodies from over 15 suppliers available with over 34 conjugates.
