STING Polyclonal / DyLight 488 /

Product Details
Description Rabbit STING/TMEM173 antibody [DyLight 488] detects Human, Mouse, Canine, Primate, Rhesus Macaque
Conjugate DyLight 488
Clone
Target Species Canine, Human, Mouse, Primate, Rhesus
Applications ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About STING
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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