Stabilin-1 Monoclonal / Unconjugated / 4G9

Product Details
Description Reacts with stabilin 1.
Conjugate Unconjugated
Clone 4G9
Target Species Human, Rat
Applications ELISA, ICC, IF, WB
Supplier Novus Biologicals
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About Stabilin-1
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq, Jul 2008]
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Validation References
PMID 28322389
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