SSB Monoclonal / Unconjugated / 1D6-H5

Product Details
Description SSB - Sjogren syndrome antigen B (autoantigen La)
Conjugate Unconjugated
Clone 1D6-H5
Target Species Human
Applications ELISA, IHC-P, WB, IHC
Supplier Novus Biologicals
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About SSB
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014]
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Validation References
PMID 18836485
PMID 23231081
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