SLC22A12 Monoclonal / Unconjugated / 2B5
Product Details
| Description | SLC22A12 - solute carrier family 22 (organic anion/cation transporter), member 12 (2B5) | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | 2B5 | |
| Target Species | Human, Mouse, Rat | |
| Applications | ELISA, ICC, IF, WB | |
| Supplier | Novus Biologicals | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About SLC22A12
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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Validation References
| PMID 21489572 | |
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| PMID 22306318 | |
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