SELENOM Polyclonal / Unconjugated /

Product Details
Description Specificity of human SELM antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About SELENOM
The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Dec 2016]
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Validation References
PMID 23880772
PMID 24519931
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