RNF8 Polyclonal / Unconjugated /
Product Details
| Description | Reacts with ring finger protein 8. | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Human, Monkey, Mouse | |
| Applications | ICC, IF, WB | |
| Supplier | Novus Biologicals | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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| Price | ||
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About RNF8
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
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Validation References
| PMID 20016594 | |
|---|---|
| PMID 25355892 | |
| PMID 26006018 | |
| PMID 26903517 | |
| Additional Sources |
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Reviews & Ratings
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