RFC4 Monoclonal / Unconjugated / 1C12

Product Details
Description RFC4 - replication factor C (activator 1) 4, 37kDa
Conjugate Unconjugated
Clone 1C12
Target Species Human
Applications ELISA, RNAi, IHC-P, WB, IHC
Supplier Novus Biologicals
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About RFC4
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
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