RAB21 Monoclonal / Unconjugated / 1G4

Product Details
Description RAB21 - RAB21, member RAS oncogene family (1G4)
Conjugate Unconjugated
Clone 1G4
Target Species Human
Applications ELISA, ICC, IF, WB
Supplier Novus Biologicals
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About RAB21
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]
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Validation References
PMID 18203561
PMID 21768288
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