Properdin Monoclonal / Unconjugated / 44128
Product Details
| Description | NB100-64677 recognizes human complement factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. NB100-64677 does not inhibit function of complement factor P. | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | 44128 | |
| Target Species | Human | |
| Applications | ELISA, WB, IHC-Fr, IHC | |
| Supplier | Novus Biologicals | |
| Catalog # | Sign in to view product details, citations, and spectra | |
| Size | ||
| Price | ||
| Antigen | ||
| Host | ||
| Isotype |
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
| Additional Sources |
|
|---|
Reviews & Ratings
| Reviews |
|---|
Looking for more options?
111 Properdin antibodies from over 12 suppliers available with over 37 conjugates.
