PRAME Monoclonal / Unconjugated / CL5148
Product Details
| Description | Specificity of human PRAME antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins. | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | CL5148 | |
| Target Species | Human | |
| Applications | IHC-P, WB, IHC | |
| Supplier | Novus Biologicals | |
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About PRAME
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
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214 PRAME antibodies from over 16 suppliers available with over 27 conjugates.
