PDE11A Polyclonal / Unconjugated /

Product Details
Description Specificity of human PDE11A antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications IHC-P, WB, IHC
Supplier Novus Biologicals
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About PDE11A
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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