MYBPC3 Polyclonal / Unconjugated /
Product Details
| Description | Human/Mouse MyBPC3 Antibody | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Human, Mouse | |
| Applications | WB | |
| Supplier | R&D Systems | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About MYBPC3
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
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Validation References
| PMID 29930088 | |
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171 MYBPC3 antibodies from over 16 suppliers available with over 27 conjugates.
