Muscleblind-like 1 Monoclonal / Alexa Fluor 700 / 1H1

Product Details
Description Mouse Muscleblind-like 1 antibody reacts with Human, Mouse (Negative), Rat (Negative) [Alexa Fluor 700]
Conjugate Alexa Fluor 700
Clone 1H1
Target Species Human, Mouse (Negative), Rat (Negative)
Applications ICC, IF, WB
Supplier Novus Biologicals
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About Muscleblind-like 1
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]
About Alexa Fluor 700
Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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