LRRFIP2 Polyclonal / Unconjugated /

Product Details
Description Rabbit LRRFIP2 antibody [Purified] detects Human, Equine, Primate
Conjugate Unconjugated
Clone
Target Species Equine, Human, Primate
Applications IHC-P, IHC
Supplier Novus Biologicals
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About LRRFIP2
The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
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