LGI1 Polyclonal / Unconjugated /

Product Details
Description This LGI1 antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications ELISA, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About LGI1
This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
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