JMJD1C Monoclonal / Unconjugated / 3A8

Product Details
Conjugate Unconjugated
Clone 3A8
Target Species Human
Applications ELISA, WB
Supplier Novus Biologicals
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About JMJD1C
The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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