CEP104 Polyclonal / Unconjugated /

Product Details
Description Specificity of human GlyBP antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Conjugate Unconjugated
Clone
Target Species Human
Applications IHC-P, IHC
Supplier Novus Biologicals
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About CEP104
This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia. [provided by RefSeq, Feb 2016]
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72 CEP104 antibodies from over 9 suppliers available with over 20 conjugates.

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