FIG4 Monoclonal / Unconjugated / S202-7

Product Details
Description 1 ug/ml of FIG4/SAC3 Antibody was sufficient for detection of FIG4/SAC3 in 20 ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary Antibody.
Conjugate Unconjugated
Clone S202-7
Target Species Human, Mouse, Rat
Applications ICC, IF, WB, IHC
Supplier Novus Biologicals
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About FIG4
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008]
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