Desert Hedgehog Monoclonal / Unconjugated / RM0087-7C8

Product Details
Description This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant protein of dhh C-terminal fragment.
Conjugate Unconjugated
Clone RM0087-7C8
Target Species Mouse
Applications WB
Supplier Novus Biologicals
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About Desert Hedgehog
This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010]
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