CD-M6PR Polyclonal / Unconjugated /

Product Details

Description	WB: Preliminary experiments gave bands at approx. 70 kDa band and 35 kDa band in human lymph node and thyroid gland lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 31.0 kDa band according to NP_002346.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). Use in Western blot reported in scientific literature (PMID: 22983091). Peptide ELISA
Conjugate	Unconjugated
Clone
Target Species	Bovine, Canine, Human, Mouse, Rat
Applications	ELISA, WB
Supplier	Novus Biologicals
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About CD-M6PR
This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]

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