CACNA2D2 Polyclonal / Unconjugated /

Product Details
Description Specificity of human CACNA2D2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications KD, IHC-P, WB, IHC
Supplier Novus Biologicals
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About CACNA2D2
Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
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100 CACNA2D2 antibodies from over 13 suppliers available with over 16 conjugates.

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