ATR Monoclonal / Unconjugated / 1000000000
Product Details
| Description | ATR - ataxia telangiectasia and Rad3 related (1E9) | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | 1000000000 | |
| Target Species | Hamster, Human, Rat | |
| Applications | ELISA, IHC-P, WB, IHC | |
| Supplier | Novus Biologicals | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About ATR
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
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Validation References
| PMID 23451157 | |
|---|---|
| PMID 25111287 | |
| PMID 25468710 | |
| PMID 29396668 | |
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Reviews & Ratings
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