CD40L Monoclonal / Janelia Fluor 646 / hu5c8 (Ruplizumab)

Product Details
Description The antibody binds to CD40L with an IC50 of 0.845 ug/ml.
Conjugate Janelia Fluor 646
Clone hu5c8 (Ruplizumab)
Target Species Human
Applications FC, WB
Supplier Novus Biologicals
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About CD40L
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
About Janelia Fluor 646
Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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