Hsp27 Monoclonal / DyLight 550 / 8A7

Product Details
Description Detects approx 25kDa or approx 27kDa. Recognizes HSP25 and HSP27, cross reacts with alpha B crystallin.
Conjugate DyLight 550
Clone 8A7
Target Species Bovine, Canine, Guinea Pig, Hamster, Human, Mouse, Rat, Sheep
Applications FC, Knockout Validated, ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About Hsp27
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
About DyLight 550
DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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