Caspase 3 Monoclonal / DyLight 550 / CPP32 4-1-18

Product Details
Description Mouse Caspase-3 antibody [DyLight 550] detects Human, Mouse, Rat
Conjugate DyLight 550
Clone CPP32 4-1-18
Target Species Human, Mouse, Rat
Applications IHC-P, WB, IHC
Supplier Novus Biologicals
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About Caspase 3
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
About DyLight 550
DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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