Desmoglein-3 Monoclonal / Biotin / 5H10

Product Details
Description Mouse Desmoglein-3 antibody [Biotin] detects Human, Mouse
Conjugate Biotin
Clone 5H10
Target Species Human, Mouse
Applications ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About Desmoglein-3
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
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