Growth Hormone R Polyclonal / Biotin /

Product Details
Description Mouse Growth Hormone R Biotinylated Antibody
Conjugate Biotin
Clone
Target Species Mouse
Applications WB, IHC
Supplier R&D Systems
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About Growth Hormone R
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
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Validation References
PMID 18945765
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315 Growth Hormone R antibodies from over 18 suppliers available with over 41 conjugates.

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