CD268 Polyclonal / Biotin /

Product Details
Description Mouse BAFFR/TNFRSF13C Biotinylated Antibody
Conjugate Biotin
Clone
Target Species Mouse
Applications ELISA, WB
Supplier R&D Systems
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About CD268
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
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Validation References
PMID 19479826
PMID 20861359
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749 CD268 antibodies from over 29 suppliers available with over 72 conjugates.

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