About STING
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

About Alexa Fluor 405
Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to V450 (BD Biosciences), Vio®Blue® (Miltenyi Biotec), Cascade Blue® (ThermoFisher Scientific), Pacific Blue® (ThermoFisher Scientific). Alexa 405 is most commonly used in flow cytometery, and fluorescence microscopy applications.