Pax3 Polyclonal / Unconjugated /

Product Details
Description Human Pax3 Antibody
Conjugate Unconjugated
Clone
Target Species Human
Applications WB, IHC
Supplier R&D Systems
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Antigen
Host
Isotype
About Pax3
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]
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Validation References
PMID 17901404
PMID 21718693
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